Name: CDK2抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： CDK2抗原（重組蛋白）

英文名稱： CDK2 Antigen (Recombinant Protein)

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Full length fusion protein

技術規(guī)格

Full name:	cyclin-dependent kinase 2
Synonyms:	p33(CDK2)
Swissprot:	P24941
Gene Accession:	BC003065
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

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