Name: FGB抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： FGB抗原（重組蛋白）

英文名稱： FGB Antigen (Recombinant Protein)

別名： HEL-S-78p

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 257 amino acids of human FGB

技術(shù)規(guī)格：

Full name:	fibrinogen beta chain
Synonyms:	HEL-S-78p
Swissprot:	P02675
Gene Accession:	BC106760
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

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