購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：SPTLC1抗原（重組蛋白）
英文名稱(chēng)： SPTLC1 Antigen (Recombinant Protein)
別 名： HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類(lèi)別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human SPTLC1 |
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Full name: |
serine palmitoyltransferase, long chain base subunit 1 |
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Synonyms: |
HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1 |
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Swissprot: |
O15269 |
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Gene Accession: |
BC068537 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. |
