購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MCAM多克隆抗體
英文名稱： Anti-MCAM rabbit polyclonal antibody
別 名： CD146, MUC18
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MCAM
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MCAM |
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Immunogen: |
Synthetic peptide of human MCAM |
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Full name: |
melanoma cell adhesion molecule |
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Synonyms: |
CD146; MUC18; HEMCAM; METCAM; MelCAM |
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SwissProt: |
P43121 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and Human ovarian cancer |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
72 kDa |
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WB Positive control: |
Human leiomyosarcoma tissue lysate |
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WB Recommended dilution: |
500-2000 |
