Name: RIC8A抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：RIC8A抗原（重組蛋白）

英文名稱： RIC8A Antigen (Recombinant Protein)

別名： RIC8

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 332-531 amino acids of human RIC8A

技術(shù)規(guī)格：

Full name:	RIC8 guanine nucleotide exchange factor A
Synonyms:	RIC8
Swissprot:	Q9NPQ8
Gene Accession:	BC011821
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

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