購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PTRF多克隆抗體
英文名稱： Anti-PTRF rabbit polyclonal antibody
別 名： CGL4; CAVIN; CAVIN1; FKSG13; cavin-1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PTRF
反應(yīng)種屬： Human Mouse Rat
標(biāo) 記 物： Unconjugate
克隆類型： Unconjugate
技術(shù)規(guī)格
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Background: |
This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. |
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Applications: |
WB |
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Name of antibody: |
PTRF |
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Immunogen: |
Synthesized peptide derived from Internal of human PTRF. |
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Full name: |
polymerase I and transcript release factor |
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Synonyms： |
CGL4; CAVIN; CAVIN1; FKSG13; cavin-1 |
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SwissProt: |
Q6NZI2 |
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WB Predicted band size: |
43 kDa |
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WB Positive control: |
Hela cells and A549 cells lysates |
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WB Recommended dilution: |
500-3000 |
