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中文名稱：兔抗RNF20多克隆抗體
英文名稱： Anti-RNF20 rabbit polyclonal antibody
別 名： BRE1; BRE1A; hBRE1
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： RNF20
反應(yīng)種屬： Human, Mouse
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
Background:
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.
Applications:
ELISA, WB, IHC
Name of antibody:
RNF20
Immunogen:
Fusion protein of human RNF20
Full name:
ring finger protein 20, E3 ubiquitin protein ligase
Synonyms：
BRE1; BRE1A; hBRE1
SwissProt:
Q5VTR2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human esophagus cancer and human colon cancer
IHC Recommend dilution:
10-50
WB Predicted band size:
114 kDa
WB Positive control:
Hela, Jurkat, 231, A375, A172 and Lovo cells
WB Recommended dilution:
500-2000
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