Name: MUC20抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MUC20抗原（重組蛋白）

英文名稱： MUC20 Antigen (Recombinant Protein)

別名： MUC-20

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MUC20

技術(shù)規(guī)格

Full name:	mucin 20, cell surface associated
Synonyms:	MUC-20
Swissprot:	Q8N307
Gene Accession:	BC029267
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

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